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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCB
All Species:
45.45
Human Site:
Y422
Identified Species:
83.33
UniProt:
P05771
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05771
NP_002729.2
671
76869
Y422
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095880
671
76836
Y422
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Dog
Lupus familis
XP_547088
663
75674
Y414
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Cat
Felis silvestris
Mouse
Mus musculus
P68404
673
76875
Y422
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Rat
Rattus norvegicus
P68403
671
76732
Y422
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510097
675
76844
Y422
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Chicken
Gallus gallus
XP_414868
670
75806
Y421
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Frog
Xenopus laevis
NP_001087142
677
77355
Y424
R
L
Y
F
V
M
E
Y
V
S
G
G
D
L
M
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
R364
A
L
N
Y
L
H
E
R
G
I
I
Y
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05130
679
77676
Y430
R
L
F
F
V
M
E
Y
V
N
G
G
D
L
M
Honey Bee
Apis mellifera
NP_001128420
673
76970
Y424
R
L
Y
F
V
M
E
Y
V
N
G
G
D
L
M
Nematode Worm
Caenorhab. elegans
P90980
682
77982
F428
R
L
Y
F
V
M
E
F
V
N
G
G
D
L
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y899
R
V
Y
F
V
M
E
Y
I
S
G
G
D
L
M
Conservation
Percent
Protein Identity:
100
N.A.
99.8
90.1
N.A.
94.6
98.8
N.A.
79.1
86.1
76.8
32.6
N.A.
66.5
70.8
65.8
N.A.
Protein Similarity:
100
N.A.
99.8
91.8
N.A.
96.2
99.2
N.A.
87.6
89.7
85.2
50.5
N.A.
80.7
81.2
78.8
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
93.3
13.3
N.A.
93.3
100
93.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
33.3
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
93
8
0
% D
% Glu:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
93
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
93
93
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
93
0
0
8
0
0
0
0
0
0
0
0
93
8
% L
% Met:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
93
% M
% Asn:
0
0
8
0
0
0
0
0
0
77
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
93
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
93
0
0
0
85
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
85
8
0
0
0
85
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _